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Excipient is a component used to obtain the desired pharmaceutical form, whether tablets, capsules, solutions or other forms of drug presentation. It is the substance responsible for completing the mass or volume of the medication, according to technical specifications.
But how to choose the best?
The raw material in which the active substances, or combinations, are added, and which are included in the pharmaceutical forms, is very important. To get your choice right, it is essential to consider that it serves as a vehicle for the active ingredient.
In addition, the excipient can help with preparation, stability and also in modifying organoleptic properties, among others. Continue reading and learn how to make the right choice. Go for the love letter iherb discount ksa there now.
What Are The Benefits Of The Excipient?
Excipient, as we mentioned above, is used to assist the drug to obtain the proper pharmaceutical form and efficiency. It aims to protect the drug against hydrolysis or oxidation, as well as to facilitate its production.
Some of the excipients support the active ingredient, since it can be found in low concentrations, requiring an extra volume. That is why they need to be pharmacologically inert substances that do not react with the drug.
What Forms Of Excipients Are Most Used?
In the pharmaceutical industry, the types of excipients most used are:
Binders: usually sugars, starches and celluloses are used, which contributes to a compressed and shaped tablet.
Sweeteners: they provide a pleasant taste to drugs.
Diluents: fill the contents of a capsule or tablet and, generally, dibasic calcium phosphate or vegetable cellulose is used as a filler.
Coverers: offer protection to the tablets against the effects of humidity and air, in addition to facilitating ingestion.
Disintegrators: as a characteristic, they expand and dissolve when in contact with water.
Lubricants: do not allow the ingredients to be bonded into grains or glued to the machines during manufacture. Commonly, silica or talc is used, in addition to steroid oils.
Dyes, flavors and flavorings: act as adjuvants to correct odor, color and unpleasant flavors, facilitating administration by the patient. Some flavorings are: menthol, anise oil, vanilla, cocoa, among others.
Coating agents: coat tablets, capsules, granules or pellets, aiming to protect the drug against possible decomposition by atmospheric moisture and oxygen, as well as mask unpleasant odors and flavors. The film used in the coating is composed of gelatin, waxes and others. Using the iherb kuwait promo code is essential in this case when you are buying the natural medicines.
How To Choose The Best Excipient For The Manipulated Medication?
It is important that the chosen excipient follows these functions:
- Allow a correct release of the active ingredient
- Provide a capsule with standard weight and content
- Ensure the stability of the preparation within the expiration date of the drug
- Please agree with the information in the pharmacopoeia monographs or other specific studies.
To make the right choice, it is essential to follow the Biopharmaceutical Classification System. However, although this is an important tool, it should not be a determining factor in the choice of excipient, nor the only factor considered.
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